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Distribution <t>of</t> <t>5-HT</t> 2C Rs in the VB and NRT. Brightfield photomicrographs showing the distribution of 5-HT 2C receptor immunoreactivity in the VB and NRT (A,D,G) , and enlarged sections of the NRT (B,E,H) and VB (C,F,I) of P25-30 NEC, GAERS and Wistar rats, as indicated. (J,K) Quantification of 5-HT <t>2C</t> <t>R</t> + neuron density in the NRT and VB of the three strains. No significant differences were observed in the NRT. In the VB, Wistar rats displayed a significantly higher 5-HT 2C R + neuron density than NEC and GAERS ( P < 0.05), with GAERS showing the lowest count ( P < 0.05). Scale bar = 200 µm in (G) (applies to (A,D,G) ) and = 50 µm in (I) (applies to (B,C,E,F,H,I) ). One-Way ANOVA with Tukey’s multiple post-test comparison (* P < 0.05).
Ht 2c R Antagonist 6 Chloro 5 Methyl N, supplied by Tocris, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/ht+2c/pmc12963287-105-9-23?v=Tocris
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mouse anti 5 ht 2 cr antibody  (Santa Cruz Biotechnology)
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Distribution <t>of</t> <t>5-HT</t> 2C Rs in the VB and NRT. Brightfield photomicrographs showing the distribution of 5-HT 2C receptor immunoreactivity in the VB and NRT (A,D,G) , and enlarged sections of the NRT (B,E,H) and VB (C,F,I) of P25-30 NEC, GAERS and Wistar rats, as indicated. (J,K) Quantification of 5-HT <t>2C</t> <t>R</t> + neuron density in the NRT and VB of the three strains. No significant differences were observed in the NRT. In the VB, Wistar rats displayed a significantly higher 5-HT 2C R + neuron density than NEC and GAERS ( P < 0.05), with GAERS showing the lowest count ( P < 0.05). Scale bar = 200 µm in (G) (applies to (A,D,G) ) and = 50 µm in (I) (applies to (B,C,E,F,H,I) ). One-Way ANOVA with Tukey’s multiple post-test comparison (* P < 0.05).
Mouse Anti 5 Ht 2 Cr Antibody, supplied by Santa Cruz Biotechnology, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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mouse anti 5 ht 2 cr antibody - by Bioz Stars, 2026-08
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ht 2c r bands  (Jackson Laboratory)
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Distribution <t>of</t> <t>5-HT</t> 2C Rs in the VB and NRT. Brightfield photomicrographs showing the distribution of 5-HT 2C receptor immunoreactivity in the VB and NRT (A,D,G) , and enlarged sections of the NRT (B,E,H) and VB (C,F,I) of P25-30 NEC, GAERS and Wistar rats, as indicated. (J,K) Quantification of 5-HT <t>2C</t> <t>R</t> + neuron density in the NRT and VB of the three strains. No significant differences were observed in the NRT. In the VB, Wistar rats displayed a significantly higher 5-HT 2C R + neuron density than NEC and GAERS ( P < 0.05), with GAERS showing the lowest count ( P < 0.05). Scale bar = 200 µm in (G) (applies to (A,D,G) ) and = 50 µm in (I) (applies to (B,C,E,F,H,I) ). One-Way ANOVA with Tukey’s multiple post-test comparison (* P < 0.05).
Ht 2c R Bands, supplied by Jackson Laboratory, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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ht 2c r bands - by Bioz Stars, 2026-08
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5 ht 2c receptor antagonist sb242084  (Tocris)
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Distribution <t>of</t> <t>5-HT</t> 2C Rs in the VB and NRT. Brightfield photomicrographs showing the distribution of 5-HT 2C receptor immunoreactivity in the VB and NRT (A,D,G) , and enlarged sections of the NRT (B,E,H) and VB (C,F,I) of P25-30 NEC, GAERS and Wistar rats, as indicated. (J,K) Quantification of 5-HT <t>2C</t> <t>R</t> + neuron density in the NRT and VB of the three strains. No significant differences were observed in the NRT. In the VB, Wistar rats displayed a significantly higher 5-HT 2C R + neuron density than NEC and GAERS ( P < 0.05), with GAERS showing the lowest count ( P < 0.05). Scale bar = 200 µm in (G) (applies to (A,D,G) ) and = 50 µm in (I) (applies to (B,C,E,F,H,I) ). One-Way ANOVA with Tukey’s multiple post-test comparison (* P < 0.05).
5 Ht 2c Receptor Antagonist Sb242084, supplied by Tocris, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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5 ht 2c r antagonist sb242084  (Tocris)
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Distribution <t>of</t> <t>5-HT</t> 2C Rs in the VB and NRT. Brightfield photomicrographs showing the distribution of 5-HT 2C receptor immunoreactivity in the VB and NRT (A,D,G) , and enlarged sections of the NRT (B,E,H) and VB (C,F,I) of P25-30 NEC, GAERS and Wistar rats, as indicated. (J,K) Quantification of 5-HT <t>2C</t> <t>R</t> + neuron density in the NRT and VB of the three strains. No significant differences were observed in the NRT. In the VB, Wistar rats displayed a significantly higher 5-HT 2C R + neuron density than NEC and GAERS ( P < 0.05), with GAERS showing the lowest count ( P < 0.05). Scale bar = 200 µm in (G) (applies to (A,D,G) ) and = 50 µm in (I) (applies to (B,C,E,F,H,I) ). One-Way ANOVA with Tukey’s multiple post-test comparison (* P < 0.05).
5 Ht 2c R Antagonist Sb242084, supplied by Tocris, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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rs-102221 5-ht 2c receptor antagonist  (Tocris)
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Distribution <t>of</t> <t>5-HT</t> 2C Rs in the VB and NRT. Brightfield photomicrographs showing the distribution of 5-HT 2C receptor immunoreactivity in the VB and NRT (A,D,G) , and enlarged sections of the NRT (B,E,H) and VB (C,F,I) of P25-30 NEC, GAERS and Wistar rats, as indicated. (J,K) Quantification of 5-HT <t>2C</t> <t>R</t> + neuron density in the NRT and VB of the three strains. No significant differences were observed in the NRT. In the VB, Wistar rats displayed a significantly higher 5-HT 2C R + neuron density than NEC and GAERS ( P < 0.05), with GAERS showing the lowest count ( P < 0.05). Scale bar = 200 µm in (G) (applies to (A,D,G) ) and = 50 µm in (I) (applies to (B,C,E,F,H,I) ). One-Way ANOVA with Tukey’s multiple post-test comparison (* P < 0.05).
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Distribution <t>of</t> <t>5-HT</t> 2C Rs in the VB and NRT. Brightfield photomicrographs showing the distribution of 5-HT 2C receptor immunoreactivity in the VB and NRT (A,D,G) , and enlarged sections of the NRT (B,E,H) and VB (C,F,I) of P25-30 NEC, GAERS and Wistar rats, as indicated. (J,K) Quantification of 5-HT <t>2C</t> <t>R</t> + neuron density in the NRT and VB of the three strains. No significant differences were observed in the NRT. In the VB, Wistar rats displayed a significantly higher 5-HT 2C R + neuron density than NEC and GAERS ( P < 0.05), with GAERS showing the lowest count ( P < 0.05). Scale bar = 200 µm in (G) (applies to (A,D,G) ) and = 50 µm in (I) (applies to (B,C,E,F,H,I) ). One-Way ANOVA with Tukey’s multiple post-test comparison (* P < 0.05).
Mk 212 5 Ht 2c Receptor Agonist, supplied by Tocris, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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5 ht 2c receptor antagonist 6 chloro 5methyl 1 2 2 methylpyridyl 3 oxy pyri 5 yl carbomyl indoline  (Tocris)
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Tocris 5 ht 2c receptor antagonist 6 chloro 5methyl 1 2 2 methylpyridyl 3 oxy pyri 5 yl carbomyl indoline
Distribution <t>of</t> <t>5-HT</t> 2C Rs in the VB and NRT. Brightfield photomicrographs showing the distribution of 5-HT 2C receptor immunoreactivity in the VB and NRT (A,D,G) , and enlarged sections of the NRT (B,E,H) and VB (C,F,I) of P25-30 NEC, GAERS and Wistar rats, as indicated. (J,K) Quantification of 5-HT <t>2C</t> <t>R</t> + neuron density in the NRT and VB of the three strains. No significant differences were observed in the NRT. In the VB, Wistar rats displayed a significantly higher 5-HT 2C R + neuron density than NEC and GAERS ( P < 0.05), with GAERS showing the lowest count ( P < 0.05). Scale bar = 200 µm in (G) (applies to (A,D,G) ) and = 50 µm in (I) (applies to (B,C,E,F,H,I) ). One-Way ANOVA with Tukey’s multiple post-test comparison (* P < 0.05).
5 Ht 2c Receptor Antagonist 6 Chloro 5methyl 1 2 2 Methylpyridyl 3 Oxy Pyri 5 Yl Carbomyl Indoline, supplied by Tocris, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Distribution of 5-HT 2C Rs in the VB and NRT. Brightfield photomicrographs showing the distribution of 5-HT 2C receptor immunoreactivity in the VB and NRT (A,D,G) , and enlarged sections of the NRT (B,E,H) and VB (C,F,I) of P25-30 NEC, GAERS and Wistar rats, as indicated. (J,K) Quantification of 5-HT 2C R + neuron density in the NRT and VB of the three strains. No significant differences were observed in the NRT. In the VB, Wistar rats displayed a significantly higher 5-HT 2C R + neuron density than NEC and GAERS ( P < 0.05), with GAERS showing the lowest count ( P < 0.05). Scale bar = 200 µm in (G) (applies to (A,D,G) ) and = 50 µm in (I) (applies to (B,C,E,F,H,I) ). One-Way ANOVA with Tukey’s multiple post-test comparison (* P < 0.05).

Journal: Frontiers in Pharmacology

Article Title: Thalamic distribution and effects of 5-HT2C receptors on tonic GABAA inhibition and absence seizures: implications for treatment

doi: 10.3389/fphar.2026.1729460

Figure Lengend Snippet: Distribution of 5-HT 2C Rs in the VB and NRT. Brightfield photomicrographs showing the distribution of 5-HT 2C receptor immunoreactivity in the VB and NRT (A,D,G) , and enlarged sections of the NRT (B,E,H) and VB (C,F,I) of P25-30 NEC, GAERS and Wistar rats, as indicated. (J,K) Quantification of 5-HT 2C R + neuron density in the NRT and VB of the three strains. No significant differences were observed in the NRT. In the VB, Wistar rats displayed a significantly higher 5-HT 2C R + neuron density than NEC and GAERS ( P < 0.05), with GAERS showing the lowest count ( P < 0.05). Scale bar = 200 µm in (G) (applies to (A,D,G) ) and = 50 µm in (I) (applies to (B,C,E,F,H,I) ). One-Way ANOVA with Tukey’s multiple post-test comparison (* P < 0.05).

Article Snippet: The 5-HT 2C R agonist (2S)-1-(6-chloro-5-fluoroindol-1-yl)propan-2-amine (Ro 60-0175), the 5-HT 2C R antagonist 6-chloro-5-methyl-N-(6-(2-methylpyridin-3-yl)oxypyridin-3-yl)-2 (SB242084) and gabazine (SR 95531 hydrobromide) were purchased from Tocris Bioscience (United Kingdom).

Techniques: Comparison